- 专利标题: COMPOSITIONS AND METHODS FOR TREATMENT
-
申请号: US14275241申请日: 2014-05-12
-
公开(公告)号: US20140371265A1公开(公告)日: 2014-12-18
- 发明人: Thomas Gadek , John Burnier , Min Zhong , Wang Shen , Johan D. Oslob , Kenneth Barr
- 申请人: SARCODE BIOSCIENCE INC.
- 申请人地址: US CA BRISBANE
- 专利权人: SARCODE BIOSCIENCE INC.
- 当前专利权人: SARCODE BIOSCIENCE INC.
- 当前专利权人地址: US CA BRISBANE
- 主分类号: C07D217/06
- IPC分类号: C07D217/06
摘要:
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists.
公开/授权文献
- US09051297B2 Compositions and methods for treatment 公开/授权日:2015-06-09
信息查询