发明申请
- 专利标题: MODIFIED MRNAS ENCODING CELL-PENETRATING POLYPEPTIDES
- 专利标题(中): 改良细胞培养多核苷酸修饰的MRNAS
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申请号: US14368070申请日: 2012-12-21
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公开(公告)号: US20140371302A1公开(公告)日: 2014-12-18
- 发明人: Noubar B. Afeyan , Gregory J. Sieczkiewicz
- 申请人: Modema Therapeutics, Inc. , Flagship Ventures
- 国际申请: PCT/US12/71118 WO 20121221
- 主分类号: C12N15/85
- IPC分类号: C12N15/85
摘要:
This invention relates to modified nucleic acid compositions encoding cell-penetrating polypeptides to provoke an innate immune response in a cell and methods of delivering protein-binding partners to target cells.
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