发明申请
- 专利标题： Heterocyclic Compounds and Methods For Their Use
- 专利标题（中）： 杂环化合物及其使用方法
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申请号： US14373355申请日： 2013-01-25
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公开(公告)号： US20150011565A1公开(公告)日： 2015-01-08
- 发明人: Thomas David McCarthy , Alan Naylor
- 申请人： Spinifex Pharmaceuticals Pty Ltd
- 优先权： AU2012900286 20120125
- 国际申请： PCT/AU2013/000061 WO 20130125
- 主分类号： C07D295/185
- IPC分类号： C07D295/185 ; C07D231/12
摘要：
The present invention relates to heterocyclic compounds useful for antagonizing angiotensin II Type 2 (AT2) receptor. More particularly the invention relates to piperazine and diazepine compounds, compositions containing them and their use in methods of treating or preventing disorders or diseases associated with AT2 receptor function including neuropathic pain, inflammatory pain, conditions associated with neuronal hypersensitivity, impaired nerve conduction velocity, cell proliferation disorders, disorders associated with an imbalance between bone resorption and bone formation and disorders associated with aberrant nerve regeneration.