Invention Application
- Patent Title: SERINE/THREONINE KINASE INHIBITORS
- Patent Title (中): 丝氨酸/螺旋激酶抑制剂
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Application No.: US14340792Application Date: 2014-07-25
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Publication No.: US20150031674A1Publication Date: 2015-01-29
- Inventor: Joachim Rudolph , Lewis J. Gazzard , James J. Crawford , Chudi Ndubaku , Joy Drobnick , Wendy Lee
- Applicant: GENENTECH, INC.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C07D471/04
- IPC: C07D471/04

Abstract:
Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
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