发明申请
- 专利标题: SERINE/THREONINE KINASE INHIBITORS
- 专利标题(中): 丝氨酸/螺旋激酶抑制剂
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申请号: US14340792申请日: 2014-07-25
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公开(公告)号: US20150031674A1公开(公告)日: 2015-01-29
- 发明人: Joachim Rudolph , Lewis J. Gazzard , James J. Crawford , Chudi Ndubaku , Joy Drobnick , Wendy Lee
- 申请人: GENENTECH, INC.
- 申请人地址: US CA South San Francisco
- 专利权人: GENENTECH, INC.
- 当前专利权人: GENENTECH, INC.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07D471/04
- IPC分类号: C07D471/04
摘要:
Compounds having the formula I wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.
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