发明申请
US20150038409A1 Leptin Compositions and Methods for Treating Progressive Cognitive Function Disorders Resulting from Accumulation of Neurofibrillary Tangles and Amyloid Beta
审中-公开
瘦素组合物和方法治疗由神经原纤维缠结和淀粉样蛋白β积累引起的进行性认知功能障碍
- 专利标题： Leptin Compositions and Methods for Treating Progressive Cognitive Function Disorders Resulting from Accumulation of Neurofibrillary Tangles and Amyloid Beta
- 专利标题（中）： 瘦素组合物和方法治疗由神经原纤维缠结和淀粉样蛋白β积累引起的进行性认知功能障碍
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申请号： US14097818申请日： 2013-12-05
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公开(公告)号： US20150038409A1公开(公告)日： 2015-02-05
- 发明人: Nikolaos Tezapsidis , Steven Greco , Mark Smith
- 申请人： Nikolaos Tezapsidis , Steven Greco , Mark Smith
- 主分类号： A61K38/22
- IPC分类号： A61K38/22 ; A61K31/7056
摘要：
The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles.