发明申请
- 专利标题： AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES
- 专利标题（中）： AZA-ARYL 1H-PYRAZOL-1-YL苯醌磺酰胺
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申请号： US14541637申请日： 2014-11-14
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公开(公告)号： US20150073017A1公开(公告)日： 2015-03-12
- 发明人: Xi CHEN , Junfa FAN , Pingchen FAN , Antoni KRASINSKI , Lianfa LI , Rebecca M. LUI , Jeffrey P. McMAHON , Jay P. POWERS , Yibin ZENG , Penglie ZHANG
- 申请人： ChemoCentryx, Inc.
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709
摘要：
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.
公开/授权文献
- US10137120B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides 公开/授权日：2018-11-27
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