Invention Application
- Patent Title: PHARMACEUTICAL FORMULATIONS OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS
- Patent Title (中): 替代酰基氨基哌啶衍生物与蛋白酶抑制剂的药物制剂
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Application No.: US14493515Application Date: 2014-09-23
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Publication No.: US20150087652A1Publication Date: 2015-03-26
- Inventor: Tao Wang , Zhongxing Zhang , Nicholas A. Meanwell , John F. Kadow , Zhiwei Yin , Qiufen May Xue , Alicia Regueiro-Ren , John D. Matiskella , Yasutsugu Ueda
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: A61K31/496
- IPC: A61K31/496 ; A61K45/06
Abstract:
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
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