- 专利标题: PROCESS FOR THE PRODUCTION OF AN ABUSE-PROOFED DOSAGE FORM
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申请号: US14564188申请日: 2014-12-09
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公开(公告)号: US20150091201A1公开(公告)日: 2015-04-02
- 发明人: ELISABETH ARKENAU-MARIC , JOHANNES BARTHOLOMÄUS
- 申请人: GRÜNENTHAL GMBH
- 申请人地址: DE AACHEN
- 专利权人: GRÜNENTHAL GMBH
- 当前专利权人: GRÜNENTHAL GMBH
- 当前专利权人地址: DE AACHEN
- 优先权: DE102005005449.8 20050204
- 主分类号: A61K9/20
- IPC分类号: A61K9/20
摘要:
The present invention relates to a process for the production of an abuse-proofed dosage form containing, apart from one or more active ingredients with potential for abuse and optionally physiologically acceptable auxiliary substances, at least one synthetic or natural polymer (C) with a breaking strength of at least 500 N, wherein the formulation mixture is combined with a solvent for the polymer (C) at least in quantities such that the formulation mixture is at least uniformly moistened, the at least moistened composition is optionally divided into sub-portions, dried and shaped to yield the dosage form.
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