An image processing apparatus includes: an imaging distance estimating unit configured to estimate an imaging distance to a subject shown in an image; an examination region setting unit configured to set an examination region in the image such that an index indicating a spread of a distribution of imaging distances to the subject shown in the examination region is within a given range; and an abnormal structure identifying unit configured to identify whether or not a microstructure of the subject shown in the examination region is abnormal, by using texture feature data that enables identification of an abnormality in the microstructure of the subject shown in the examination region, the texture feature data being specified according the examination region.