In one aspect, a system for reducing noise or vibration generated by an internal combustion engine is described. An engine controller is arranged to generate firing information suitable for operating the working chambers of the engine in a skip fire manner to deliver a desired amount of torque. A noise/vibration reduction unit is arranged to help reduce noise or vibration based on the firing information. The noise/vibration controller actively controls a device that is not a part of the engine to alter an NVH characteristic of the vehicle in a desired manner based at least in part on a skip fire characteristic.