发明申请
US20150105296A1 HYDROXY-SPHINGOMYELIN 22:1 AS A BIOMARKER FOR HEALTHY AGING
审中-公开
羟脯氨酸22：1作为健康老化的生物标记
- 专利标题： HYDROXY-SPHINGOMYELIN 22:1 AS A BIOMARKER FOR HEALTHY AGING
- 专利标题（中）： 羟脯氨酸22：1作为健康老化的生物标记
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申请号： US14491691申请日： 2014-09-19
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公开(公告)号： US20150105296A1公开(公告)日： 2015-04-16
- 发明人: Sebastiano Collino , Ivan Montoliu Roura , Francois-Pierre Martin , Philippe Alexandre Guy , Serge Andre Dominique Rezzi
- 申请人： Nestec S.A.
- 优先权： EP12160740.2 20120322
- 主分类号： G01N33/92
- IPC分类号： G01N33/92 ; G01N33/50 ; G01N33/68
摘要：
Using NMR/MS based metabonomics and targeted lipidomics approaches the inventors have explored the metabolic phenotypes of aging and longevity in a cohort compromising centenarians, elderly and young adults. The inventors have identified biomarkers for a reduced risk of developing ageing related chronic inflammatory disorders and propose a method of diagnosing a lifestyle that allows delaying and/or avoiding ageing related chronic inflammatory disorders using hydroxy-sphingomyelin SM-OH-22:1 as biomarker.
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