Invention Application
US20150133463A1 MULTICOMPONENT CRYSTALS COMPRISING DASATINIB AND SELECTED CO-CRYSTAL FORMERS
有权
包含DASATINIB和选择的CO晶体形成的多组分晶体
- Patent Title: MULTICOMPONENT CRYSTALS COMPRISING DASATINIB AND SELECTED CO-CRYSTAL FORMERS
- Patent Title (中): 包含DASATINIB和选择的CO晶体形成的多组分晶体
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Application No.: US14406339Application Date: 2013-06-13
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Publication No.: US20150133463A1Publication Date: 2015-05-14
- Inventor: Tiziana Chiodo , Andreas Hafner , Tobias Hintermann , Beate Salvador , Martin Szelagiewicz , Fritz Blatter , Bernd Siebenhaar , Marcus Vossen
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Priority: EP12172172.4 20120615
- International Application: PCT/IB2013/054832 WO 20130613
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D213/82 ; A61K31/506 ; C07C47/58 ; C07C35/12 ; C07C65/03 ; C07D309/40

Abstract:
Provided are a multicomponent crystalline system (co-crystal), use thereof, as well as a process for obtaining the same. The said multicomponent crystalline system (co-crystal) comprises Dasatinib and a second compound selected from methyM-hydrobenzoate, nicotinamide, ethyl gallate, methyl gallate, propyl gallate, ethyl maltol, vanillin, menthol, or (1R,2S,5R)-(−)-menthol.
Public/Granted literature
- US09340536B2 Multicomponent crystals comprising dasatinib and selected co-crystal formers Public/Granted day:2016-05-17
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