Invention Application
US20150175536A1 HEMIFUMARATE SALT OF 1-[4-[1-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXYIMINO)-ETHYL]-2-ETHYL-BENZYL]-AZETIDINE-3-CARBOXYLIC ACID
审中-公开
1- [4- [1-（4-环丙基-3-三氟甲基 - 苯甲酰基） - 乙基] -2-乙基苯基] - 三羟甲基-3-羧酸的盐酸盐
![HEMIFUMARATE SALT OF 1-[4-[1-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXYIMINO)-ETHYL]-2-ETHYL-BENZYL]-AZETIDINE-3-CARBOXYLIC ACID](/docs/US/2015-06-25/US20150175536A1/abs.jpg.600x600.jpg)
- Patent Title: HEMIFUMARATE SALT OF 1-[4-[1-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXYIMINO)-ETHYL]-2-ETHYL-BENZYL]-AZETIDINE-3-CARBOXYLIC ACID
- Patent Title (中): 1- [4- [1-（4-环丙基-3-三氟甲基 - 苯甲酰基） - 乙基] -2-乙基苯基] - 三羟甲基-3-羧酸的盐酸盐
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Application No.: US14636248Application Date: 2015-03-03
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Publication No.: US20150175536A1Publication Date: 2015-06-25
- Inventor: Lech CISZEWSKI , Marilyn DE LA CRUZ , Piotr H. KARPINSKI , Michael MUTZ , Christian RIEGERT , Caspar VOGEL , Ricardo SCHNEEBERGER
- Applicant: Lech CISZEWSKI , Marilyn DE LA CRUZ , Piotr H. KARPINSKI , Michael MUTZ , Christian RIEGERT , Caspar VOGEL , Ricardo SCHNEEBERGER
- Main IPC: C07D205/04
- IPC: C07D205/04
![HEMIFUMARATE SALT OF 1-[4-[1-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXYIMINO)-ETHYL]-2-ETHYL-BENZYL]-AZETIDINE-3-CARBOXYLIC ACID](/abs-image/US/2015/06/25/US20150175536A1/abs.jpg.150x150.jpg)
Abstract:
This invention relates to a hemifumarate salt of 1-(4-{1-[(E)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl)-azetidine-3-carboxylic acid (Compound I), to pharmaceutical compositions comprising this salt, to processes for forming this salt and to its use in medical treatment. In addition, the present invention also relates to new polymorphic forms of the hemifumarate salt form of Compound I, as well as to pharmaceutical compositions comprising these polymorphic forms, to processes for obtaining them, and their use in medical treatment.
Information query
