Invention Application
- Patent Title: IMIDAZOLYL ANALOGS AS SYK INHIBITORS
- Patent Title (中): 咪唑啉类似物作为SYK抑制剂
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Application No.: US14409147Application Date: 2013-06-18
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Publication No.: US20150175575A1Publication Date: 2015-06-25
- Inventor: Jongwon Lim , Michael H. Reutershan , John Michael Ellis , Kaleen Konrad Childers , Anthony Donofrio , Michael D. Altman , Andrew M. Haidle , Anna Zabierek , Matthew Christopher , Jonathan Grimm , Jason Burch , Maria Emilia Di Francesco , Alessia Petrocchi , Christian Beaulieu , Vouy Linh Truong , Alan B. Northrup , Marc Blouin
- Applicant: Merck Sharp & Dohme Corp. , Merck Canada Inc.
- International Application: PCT/US13/46223 WO 20130618
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/14
Abstract:
The present invention provides novel imidazole analogs of Formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.
Public/Granted literature
- US09487504B2 Imidazolyl analogs as syk inhibitors Public/Granted day:2016-11-08
Information query
