发明申请
US20150183761A1 BENZIMIDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS
审中-公开
苯并咪唑羧酰胺化合物作为5-HT4受体激动剂
- 专利标题： BENZIMIDAZOLE-CARBOXAMIDE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS
- 专利标题（中）： 苯并咪唑羧酰胺化合物作为5-HT4受体激动剂
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申请号： US14488520申请日： 2014-09-17
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公开(公告)号： US20150183761A1公开(公告)日： 2015-07-02
- 发明人: Robert Murray McKinnell , Lan Jiang , Daniel D. Long
- 申请人： Robert Murray McKinnell , Lan Jiang , Daniel D. Long
- 申请人地址： US CA South San Francisco
- 专利权人： THERAVANCE BIOPHARMA R&D IP, LLC
- 当前专利权人： THERAVANCE BIOPHARMA R&D IP, LLC
- 当前专利权人地址： US CA South San Francisco
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D409/14 ; C07D405/14
摘要：
The invention relates to benzimidazole-carboxamide 5-HT4 receptor agonist compounds of formula (I) wherein R1 and X are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.
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