Invention Application
- Patent Title: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
- Patent Title (中): 用于治疗癌症和免疫和自发性疾病的病毒诱导剂
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Application No.: US14582144Application Date: 2014-12-23
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Publication No.: US20150183775A1Publication Date: 2015-07-02
- Inventor: Milan BRUNCKO , Yujia DAI , Hong DING , George A. DOHERTY , Steven W. ELMORE , Lisa HASVOLD , Laura HEXAMER , Aaron R. KUNZER , Robert A. MANTEI , Chang H. PARK , Cheol-Min PARK , Andrew M. PETROS , Xiaohong SONG , Andrew J. SOUERS , Gerard M. SULLIVAN , Zhi-Fu TAO , Gary T. WANG , Le WANG , Xilu WANG , Michael D. WENDT , William J. MCCLELLAN
- Applicant: AbbVie Inc.
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D405/12 ; C07D413/12 ; C07D401/12

Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Public/Granted literature
- US09303025B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Public/Granted day:2016-04-05
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