发明申请
- 专利标题: Controlled Release Formulations of Lorazepam
- 专利标题(中): 洛拉西泮控释制剂
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申请号: US14150493申请日: 2014-01-08
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公开(公告)号: US20150190345A1公开(公告)日: 2015-07-09
- 发明人: Douglas A. Saltel , Michael Vachon
- 申请人: Douglas A. Saltel , Michael Vachon
- 主分类号: A61K9/20
- IPC分类号: A61K9/20 ; A61K31/5513
摘要:
Controlled release of lorazepam can provide enhanced dosing options including once daily dosing that provides 24 hour therapeutic effect under steady state conditions. The pharmaceutical composition can provide substantially zero order release and 90% release within 7 to 12 hours in a pharmaceutical dissolution test. The release can be achieved using polyethylene oxide as a matrix polymer.