Invention Application
US20150196511A1 COMPOSITION COMPRISING METFORMIN AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE
有权
包含METFORMIN作为活性成分用于预防或治疗炎症性皮肤疾病的组合物
- Patent Title: COMPOSITION COMPRISING METFORMIN AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE
- Patent Title (中): 包含METFORMIN作为活性成分用于预防或治疗炎症性皮肤疾病的组合物
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Application No.: US14663235Application Date: 2015-03-19
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Publication No.: US20150196511A1Publication Date: 2015-07-16
- Inventor: Mi-La Cho , Seon-Yeong Lee , Eun-Ji Yang , Hye-Jin Son , Eun-Kyung Kim , Jun-Geol Ryu
- Applicant: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
- Priority: KR10-2012-0104969 20120921; KR10-2013-0111679 20130917
- Main IPC: A61K31/155
- IPC: A61K31/155 ; A61K39/395
Abstract:
The present invention relates to a composition comprising metformin as an active ingredient for preventing or treating inflammatory bowel disease. The metformin compound or the metformin-etanercept (product name: Enbrel) composite according to the present invention may have excellent effects of maintaining the thickness of the small intestine and length of the large intestine normal, inhibiting or decreasing the activity of IL-17 and TNF-a, and promoting or increasing the activity of IFNr, and therefore can be effectively used as a pharmaceutical composition for preventing or treating autoimmune diseases including inflammatory bowel disease.
Public/Granted literature
- US09700531B2 Composition comprising metformin as active ingredient for preventing or treating inflammatory bowel disease Public/Granted day:2017-07-11
Information query
