Devices, systems and methods are described for mitigating interference in a wireless communications network. In particular, the network may be a Wi-Fi network. Multiple approaches may be implemented to mitigate ACI. Further, multiple approaches may be implemented to mitigate non-Wi-Fi interference as well. Each of the approaches may consist of two parts, namely, interference detection and interference mitigation (or reduction). One approach may involve: detecting adjacent channel interference (ACI) in an operating channel of the device; determining a location of the detected ACI in an operating band of the device; and mitigating the detected ACI by communicating via a channel different from the operating channel, the different channel being determined to be further away from the location of the detected ACI.