Invention Application
US20150202271A1 DNA VACCINE CONTAINING VEGF-SPECIFIC EPITOPE AND/OR ANGIOPOIETIN-2-SPECIFIC EPITOPE
审中-公开
含有VEGF特异性抗原决定簇和/或抗血清素-2特异性抗原决定簇的DNA疫苗
- Patent Title: DNA VACCINE CONTAINING VEGF-SPECIFIC EPITOPE AND/OR ANGIOPOIETIN-2-SPECIFIC EPITOPE
- Patent Title (中): 含有VEGF特异性抗原决定簇和/或抗血清素-2特异性抗原决定簇的DNA疫苗
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Application No.: US14424937Application Date: 2013-08-28
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Publication No.: US20150202271A1Publication Date: 2015-07-23
- Inventor: Hironori Nakagami , Mariko Kyutoku , Ryuichi Morishita , Hideki Tomioka
- Applicant: OSAKA UNIVERSITY , ANGES MG, INC.
- Priority: JP2012-191717 20120831
- International Application: PCT/JP2013/073045 WO 20130828
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N7/00
Abstract:
The present invention provides a therapeutic or prophylactic agent for cancer, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of VEGF and/or a specific epitope of angiopoietin-2, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
Public/Granted literature
- US10543261B2 DNA vaccine containing VEGF-specific epitope and/or angiopoietin-2-specific epitope Public/Granted day:2020-01-28
Information query
