Invention Application
- Patent Title: Imidazopyridine Derivatives as Modulators of TNF Activity
- Patent Title (中): 咪唑并吡啶衍生物作为TNF活性的调节剂
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Application No.: US14414287Application Date: 2013-07-05
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Publication No.: US20150203486A1Publication Date: 2015-07-23
- Inventor: Jonathan Mark Bentley , Daniel Christopher Brookings , Julien Alistair Brown , Thomas Paul Cain , Praful Tulshi Chovatia , Anne Marie Foley , Ellen Olivia Gallimore , Laura Jane Gleave , Alexander Heifetz , Helen Tracey Horsley , Martin Clive Hutchings , Victoria Elizabeth Jackson , James Andrew Johnson , Craig Johnstone , Boris Kroeplien , Fabien Claude Lecomte , Deborah Leigh , Martin Alexander Lowe , James Madden , John Robert Porter , Joanna Rachel Quincey , Laura Claire Reed , James Thomas Reuberson , Anthony John Richardson , Sarah Emily Richardson , Matthew Duncan Selby , Michael Alan Shaw , Zhaoning Zhu
- Applicant: UCB Biopharma SPRL
- Assignee: UCB Biopharma SPRL a corporation
- Current Assignee: UCB Biopharma SPRL a corporation
- Priority: GB1212512.6 20120713; GB1221920.0 20121205
- International Application: PCT/EP2013/064331 WO 20130705
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/496 ; A61K31/506 ; C07D491/107 ; A61K31/5377 ; A61K31/5513 ; A61K31/554 ; A61K31/437 ; A61K31/541
Abstract:
A series of imidazo[1,2-a]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
Public/Granted literature
- US09309243B2 Imidazopyridine derivatives as modulators of TNF activity Public/Granted day:2016-04-12
Information query
