DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF

Invention Application

US20150232550A1 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开

Title translation: 双变量域免疫球蛋白及其用途

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Patent Title: DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF
Patent Title (中): 双变量域免疫球蛋白及其用途
Application No.: US14689914

Application Date: 2015-04-17
Publication No.: US20150232550A1

Publication Date: 2015-08-20
Inventor: Tariq Ghayur , Jochen G. Salfeld , Michael J. McPherson
Applicant: AbbVie Inc.
Main IPC: C07K16/24
IPC: C07K16/24 ; G01N33/68 ; C07K16/18 ; A61K39/395 ; A61K45/06

DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF

Abstract:

Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided.

Abstract(Chinese):

提供了工程化的多价和多特异性结合蛋白，制备方法及其在预防，诊断和/或治疗疾病中的用途。

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Global Dossier Espacenet

IPC分类:

C	化学；冶金
C07	有机化学
C07K	肽（含有β-内酰胺的肽入C07D；在分子中除了形成本身的肽环外不含有任何其他的肽键的环状二肽，如哌嗪-2,5-二酮入C07D；环肽型麦角生物碱入C07D519/02；单细胞蛋白质、酶入C12N；获得肽的基因工程方法入C12N15/00）
C07K16/00	免疫球蛋白，例如，单克隆或多克隆抗体
C07K16/18	.抗来自动物或人的物质
C07K16/24	..抗细胞因子，淋巴因子或干扰素