发明申请
US20150239902A1 Novel Imidazol-piperidinyl Derivatives as Modulators of Kinase Activity
有权
新型咪唑 - 哌啶衍生物作为激酶活性的调节剂
- 专利标题: Novel Imidazol-piperidinyl Derivatives as Modulators of Kinase Activity
- 专利标题(中): 新型咪唑 - 哌啶衍生物作为激酶活性的调节剂
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申请号: US14432319申请日: 2013-11-15
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公开(公告)号: US20150239902A1公开(公告)日: 2015-08-27
- 发明人: Ruoxi Lan , Bayard R. Huck , Xiaoling Chen , Yufang Xiao
- 申请人: Ruoxi LAN , Bayard R. HUCK , Xiaoling CHEN , Yufang XIAO , MERCK PATENT GMBH
- 国际申请: PCT/US2013/070258 WO 20131115
- 主分类号: C07D498/04
- IPC分类号: C07D498/04 ; C07D487/04 ; A61K31/519 ; A61K45/06 ; A61K31/517 ; C07D471/04 ; A61K31/4375 ; A61K31/5383 ; C07D401/14
摘要:
The invention provides novel imidazol-piperidinyl derivatives of formula (I) in which R1, R2, X1, X2, X3, X4 and n have the meanings indicated in above, and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.