Invention Application
- Patent Title: NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME
- Patent Title (中): 新型螺旋衍生物及其生产方法
-
Application No.: US14431935Application Date: 2013-10-04
-
Publication No.: US20150246927A1Publication Date: 2015-09-03
- Inventor: Hai-Lei Cui , Fujie Tanaka
- Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Applicant Address: JP Okinawa
- Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Current Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION
- Current Assignee Address: JP Okinawa
- International Application: PCT/JP2013/077682 WO 20131004
- Main IPC: C07D491/107
- IPC: C07D491/107
Abstract:
Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.
Public/Granted literature
- US09309261B2 Spirooxindole derivative and process for producing the same Public/Granted day:2016-04-12
Information query
