发明申请
US20150259380A1 Truncated LYP-1 Peptides and Methods and Compositions Using Truncated LYP-1 Peptides
审中-公开
截短的LYP-1肽和使用截短的LYP-1肽的方法和组合物
- 专利标题: Truncated LYP-1 Peptides and Methods and Compositions Using Truncated LYP-1 Peptides
- 专利标题(中): 截短的LYP-1肽和使用截短的LYP-1肽的方法和组合物
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申请号: US13594194申请日: 2012-08-24
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公开(公告)号: US20150259380A1公开(公告)日: 2015-09-17
- 发明人: Erkki Ruoslahti , Tambet Teesalu , Kazuki Sugahara , Lise Roth
- 申请人: Erkki Ruoslahti , Tambet Teesalu , Kazuki Sugahara , Lise Roth
- 申请人地址: US CA La Jolla
- 专利权人: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- 当前专利权人: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
- 当前专利权人地址: US CA La Jolla
- 主分类号: C07K7/06
- IPC分类号: C07K7/06 ; A61K38/10 ; A61K31/337 ; A61K47/48
摘要:
Disclosed are compositions and methods useful for targeting and internalizing molecules into cells of interest and for penetration by molecules of tissues of interest. The compositions and methods are based on peptide sequences, such as truncated LyP-1 peptides, that are selectively internalized by a cell, penetrate tissue, or both. The disclosed internalization and tissue penetration is useful for delivering therapeutic and detectable agents to cells and tissues of interest.