发明申请
US20150259675A1 SHORT INTERFERING RIBONUCLEIC ACID (siRNA) FOR ORAL ADMINISTRATION
审中-公开
用于口服管理的短暂的干扰素(siRNA)
- 专利标题: SHORT INTERFERING RIBONUCLEIC ACID (siRNA) FOR ORAL ADMINISTRATION
- 专利标题(中): 用于口服管理的短暂的干扰素(siRNA)
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申请号: US14177640申请日: 2014-02-11
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公开(公告)号: US20150259675A1公开(公告)日: 2015-09-17
- 发明人: Francois Jean-Charles NATT , Eric BILLY , Juerg HUNZIKER , Christian Rene SCHNELL
- 申请人: Francois Jean-Charles NATT , Eric BILLY , Juerg HUNZIKER , Christian Rene SCHNELL
- 申请人地址: CH Basel
- 专利权人: NOVARTIS AG
- 当前专利权人: NOVARTIS AG
- 当前专利权人地址: CH Basel
- 主分类号: C12N15/113
- IPC分类号: C12N15/113
摘要:
Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which strands contains at least one chemical modification.