Invention Application
- Patent Title: IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF
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Application No.: US14581971Application Date: 2014-12-23
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Publication No.: US20150266953A1Publication Date: 2015-09-24
- Inventor: Jian CHEN , Ellen FILVAROFF , Sherman FONG , Dorothy FRENCH , Audrey GODDARD , Paul J. GODOWSKI , J. Christopher GRIMALDI , Austin L. GUMEY , Kenneth J. HILLAN , Sarah G. HYMOWITZ , Hanzhong LI , James Pan ZTUBICOKE , Melissa A. STAROVASNIK , Daniel TUMAS , Menno VAN LOOKEREN , Richard VANDLEN , Colin K. WATANABE , P. Mickey WILLIAMS , William I. WOOD , Daniel G. YANSURA
- Applicant: GENENTECH, INC.
- Applicant Address: US CA South San Francisco
- Assignee: GENENTECH, INC.
- Current Assignee: GENENTECH, INC.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K14/54
Abstract:
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Information query
