A method includes estimating, for a given battery cell of a plurality of battery cells, an internal resistance, estimating, for the given battery cell, an open-circuit voltage, determining a target output voltage for the given battery cell, determining a target discharge current for the given battery cell, determining a target internal resistance for the given battery cell based on the estimated open-circuit voltage for the given battery cell, the target output voltage for the given battery cell, and the target discharge current for the given battery cell, determining a target cell temperature for the given battery cell based on the target internal resistance for the given battery cell, and controlling a flow of coolant adjacent to the given battery cell based on the target temperature for the given battery cell.