发明申请
- 专利标题: Polysialic Acid Derivatives
- 专利标题(中): 聚唾液酸衍生物
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申请号: US14791468申请日: 2015-07-05
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公开(公告)号: US20150307633A1公开(公告)日: 2015-10-29
- 发明人: Dale Howard Hreczuk-Hirst , Sanjay Jain , Peter Laing , Gregory Gregoriadis , Ioannis Papaioannou
- 申请人: Lipoxen Technologies Limited
- 申请人地址: US MA Lexington
- 专利权人: LIPOXEN TECHNOLOGIES LIMITED
- 当前专利权人: LIPOXEN TECHNOLOGIES LIMITED
- 当前专利权人地址: US MA Lexington
- 优先权: EP03254988.3 20030812; EP03255200.2 20030821
- 主分类号: C08B37/00
- IPC分类号: C08B37/00 ; C12N9/96 ; C07K17/10
摘要:
A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.
公开/授权文献
- US09920137B2 Polysialic acid derivatives 公开/授权日:2018-03-20