Invention Application
- Patent Title: Use of DR6 Antagonists to Improve Motor Neuron Disease
- Patent Title (中): 使用DR6拮抗剂改善运动神经元疾病
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Application No.: US14655126Application Date: 2013-12-27
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Publication No.: US20150329638A1Publication Date: 2015-11-19
- Inventor: Sha MI
- Applicant: BIOGEN IDEC MA INC.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2013/078081 WO 20131227
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K45/06
Abstract:
The present invention relates to Death Receptor-6 (DR6) antagonists and methods of their use in improving motor neuron disease. Novel affinity enhanced anti-DR6 antibodies are also provided. The invention also pertains to methods of identifying additional anti-DR6 antagonists.
Public/Granted literature
- US1780613A Regulating device for liquid couplings Public/Granted day:1930-11-04
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