Provided are a gas communication device, a gas supply assembly and a gas supply adjustment method. The gas communication device is connectable to a gas supplier and comprises a main body, an engagement member, a press member and a release member. The press member drives the disengagement of the engagement member from the gas supplier, and the release member is structurally changeable to promote easy removal of the gas communication device from the gas supplier. The gas supply assembly is a combination of the gas communication device and the gas supplier. The gas supply adjustment method is applicable to the adjustment of gas supply and gas exhaust between the gas supply assembly and an air mattress and is characterized by making use of the structural change of the release member to promote the removal of the gas communication device from the gas supplier.