发明申请
US20160031890A1 NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS
有权
用于抑制ROS的新方法，化合物和组合物
- 专利标题： NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS
- 专利标题（中）： 用于抑制ROS的新方法，化合物和组合物
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申请号： US14775825申请日： 2013-03-14
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公开(公告)号： US20160031890A1公开(公告)日： 2016-02-04
- 发明人: DORRE A. GRUENEBERG , ORI KALID , JUN XIAN , SHARANAPPA B. RAJUR , HWA-OK KIM , VENUGOPAL RAO NEELAGIRI , PARESH SALGAONKAR , DIVAKARAMENON SETHUMADHAVAN , CHAEHO MOON , MADHAVI NEELAGIRI
- 申请人： Dorre A. GRUENEBERG , Ori KALID , Jun XIAN , Sharanappa B. RAJUR , Hwa-ok KIM , Venugopal Rao NEELAGIRI , Paresh GAONKAR , Divakaramenon MADHAVAN , Chaeho MOON , Madhavi NEELAGIRI
- 国际申请： PCT/IB2014/059733 WO 20130314
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K45/06 ; A61K31/506 ; C07D403/12 ; C07D409/14 ; C07D417/14 ; C07D417/12 ; A61K31/53 ; C07D209/08 ; A61K31/404 ; A61K31/497 ; C07D471/04 ; A61K31/4375 ; C07D243/14 ; A61K31/551 ; C07D401/14 ; A61K31/454 ; A61K31/519
摘要：
The present invention relates to a method using some novel compounds and compositions for the inhibition of ROS tyrosine kinase. In particular, the present invention covers a method to treat abnormal cell growth, such as cancer, with ROS 10 inhibitors and compositions having ROS inhibitors. An illustrative compound of the invention is shown below Formula (I).
公开/授权文献
- US09963452B2 Methods, compounds, and compositions for inhibition of ROS 公开/授权日：2018-05-08