发明申请
- 专利标题： QUANTITATIVE ASSESSMENT FOR CAP EFFICIENCY OF MESSENGER RNA
- 专利标题（中）： 定量评估信使RNA的效率
-
申请号： US14775846申请日： 2014-03-14
-
公开(公告)号： US20160032356A1公开(公告)日： 2016-02-04
- 发明人: Michael Heartlein , Frank DeRosa , Anusha Dias
- 申请人： SHIRE HUMAN GENETIC THERAPIES, INC.
- 国际申请： PCT/US14/27587 WO 20140314
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07K14/505 ; C12N9/02
摘要：
The present invention provides, among other things, methods of quantitating mRNA capping efficiency, particularly for mRNA synthesized in vitro. In some embodiments, the methods comprise chromatographic methods of quantifying capping efficiency and methylation status of the caps.
公开/授权文献
- US09970047B2 Quantitative assessment for cap efficiency of messenger RNA 公开/授权日：2018-05-15
信息查询
