A method of driving a display panel is proposed. The method includes determining whether an input image data represents a video image or a static image, determining whether an image transition occurs in the input image data when the input image data represents the static image, and inserting a plurality of image sticking compensation frames between normal frames in a low frequency driving when the image transition occurs in the input image data between the normal frames. The number of the image sticking compensation frame may be properly adjusted during a cycle of low frequency driving.