A mobile device and method for a messenger-based video call service using camera preview image and voice information are provided. In the method, the mobile device displays a camera preview screen by executing a camera, and detects an input for selecting one or more sharers for a video call from the camera preview screen. Then, the mobile device executes a messenger for providing the video call service, transmits a connection request to the selected sharers through the messenger, and performs the messenger-based video call with the sharers in response to the connection request.