发明申请
- 专利标题: PYRAZOLO COMPOUNDS AND USES THEREOF
- 专利标题(中): 吡咯化合物及其用途
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申请号: US14775405申请日: 2014-03-13
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公开(公告)号: US20160060267A1公开(公告)日: 2016-03-03
- 发明人: Brian K. Albrecht , Steven F. Bellon , Victor S. Gehling , Jean-Christophe Harmange , Kwong Wah Lai , Jun Liang , Peter Dragovich , Dan Ortwine , Sharada Labadie , Birong Zhang , Jim Kiefer
- 申请人: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
- 申请人地址: US CA South San Francisco US MA Cambridge
- 专利权人: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- 当前专利权人: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- 当前专利权人地址: US CA South San Francisco US MA Cambridge
- 国际申请: PCT/CN2014/000262 WO 20140313
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K45/06 ; C12N9/99 ; A61K31/337 ; A61K31/517 ; A61K31/437 ; A61K31/519 ; A61K31/5377
摘要:
Provided are compounds useful as inhibitors of one or more histone demethylases, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using the present composition in the treatment of various disorders.
公开/授权文献
- US10035801B2 Pyrazolo compounds and uses thereof 公开/授权日:2018-07-31
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