发明申请
US20160082640A1 HOT MELT FRAGMENTATION EXTRUDER AND PROCESS 有权
热熔胶分层挤出机和工艺

HOT MELT FRAGMENTATION EXTRUDER AND PROCESS
摘要:
A co-rotating twin screw extruder for forming fragments is disclosed. The extruder comprises of an intake zone for receiving one or more excipient(s) suitable for oral dosage or one or more excipient(s) suitable for oral dosage along with one or more active pharmaceutical ingredient, a melt zone for softening at least one excipient to form a viscous mass or melt and a fragmenting zone for fragmenting and cooling the viscous mass into cooled fragments and an extruder outlet for recovering the cooled fragments from the extruder.
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