A system for optimized image acquisition includes an user interface for receiving a first input indicating a selection of an anatomical region of a subject and receiving a second input indicating a selection of at least one feature of interest and at least one appropriate property of the at least one feature of interest. Further, the system includes a scanning unit for moving the subject to isocenter of a magnet and acquiring at least one image of the anatomical region of the subject. Also, the system includes a processor for processing the at least one image for identifying the at least one feature of interest in the at least one image, wherein the scanning unit is configured to re-scan the at least one feature of interest using the at least one selected appropriate property for acquiring an optimized image of the at least one feature of interest.