发明申请
US20160090382A1 Substituted 1 H-Pyrrolo [2, 3-b] pyridine and 1 H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors
有权
取代的1 H-吡咯并[2,3-b]吡啶和1 H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
![Substituted 1 H-Pyrrolo [2, 3-b] pyridine and 1 H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors](/docs/US/2016-03-31/US20160090382A1/abs.jpg.600x600.jpg)
- 专利标题： Substituted 1 H-Pyrrolo [2, 3-b] pyridine and 1 H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors
- 专利标题（中）： 取代的1 H-吡咯并[2,3-b]吡啶和1 H-吡唑并[3,4-b]吡啶衍生物作为盐诱导型激酶2（SIK2）抑制剂
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申请号： US14958625申请日： 2015-12-03
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公开(公告)号： US20160090382A1公开(公告)日： 2016-03-31
- 发明人: Hariprasad Vankayalapati , Venkatakrishnareddy Yerramreddy , Venu Babu Ganipisetty , Sureshkumar Talluri , Rajendra P Appalaneni
- 申请人： Arrien Pharmaceuticals LLC
- 主分类号： C07D471/04
- IPC分类号： C07D471/04
![Substituted 1 H-Pyrrolo [2, 3-b] pyridine and 1 H-Pyrazolo [3, 4-b] pyridine Derivatives as Salt Inducible Kinase 2 (SIK2) Inhibitors](/abs-image/US/2016/03/31/US20160090382A1/abs.jpg.150x150.jpg)
摘要：
Compounds according to Formulas I, IA or IB: to pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and/or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.
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