Examples of systems and methods for multisensory change detection are generally described herein. A method may include receiving a first set of signals from a first combination of sensors and a second set of signals from a second combination of sensors in a plurality of sensors, and determining a first distribution for the first set of signals and a second distribution for the second set of signals. The method may include estimating a divergence between the first and second distributions using the first and second combinations of sensors, a count of the plurality of sensors, and distances from a plurality of signals in the second set of signals to a first plurality of nearest neighbor signals in the first set of signals and a second plurality of nearest neighbor signals in the second set of signals. The method may include determining whether the divergence exceeds a threshold.