发明申请
- 专利标题： CHIMERIC ANTIGEN RECEPTOR-TARGETING MONOCLONAL ANTIBODIES
- 专利标题（中）： CHIMERIC抗原受体靶向单克隆抗体
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申请号： US14893223申请日： 2014-05-23
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公开(公告)号： US20160096902A1公开(公告)日： 2016-04-07
- 发明人: Laurence JN COOPER , Bipulendu JENA , Harjeet SINGH , David RUSHWORTH
- 申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 申请人地址： US TX Austin
- 专利权人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 当前专利权人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 当前专利权人地址： US TX Austin
- 国际申请： PCT/US2014/039365 WO 20140523
- 主分类号： C07K16/42
- IPC分类号： C07K16/42 ; G01N33/566
摘要：
Provided are monoclonal antibodies that detect CD 19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they target. Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.
公开/授权文献
- US09701758B2 Anti-CD19 scFv (FMC63) polypeptide 公开/授权日：2017-07-11
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