Invention Application
- Patent Title: Methods of using Microneedle Vaccine Formulations to Elicit in Animals Protective Immunity against Rabies Virus
- Patent Title (中): 使用微针疫苗制剂诱发动物免疫狂犬病毒的方法
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Application No.: US14930831Application Date: 2015-11-03
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Publication No.: US20160120799A1Publication Date: 2016-05-05
- Inventor: Yu-Wei Chiang , Mark R. Prausnitz , Kristopher Daniel DeWitt , Jaya Arya
- Applicant: MERIAL, INC. , Georgia Tech Research Corporation
- Applicant Address: US GA Atlanta US GA DULUTH
- Assignee: GEORGIA TECH RESEARCH CORPORATION,MERIAL, INC.
- Current Assignee: GEORGIA TECH RESEARCH CORPORATION,MERIAL, INC.
- Current Assignee Address: US GA Atlanta US GA DULUTH
- Main IPC: A61K9/00
- IPC: A61K9/00 ; C12N7/00 ; A61K39/205

Abstract:
The present invention relates to microneedle vaccine formulations, as well as methods of use thereof to provide animals, including canines, protective immunity against infection and disease caused by rabies viruses. Once placed onto the skin of the animals, the microneedle formulations dissolve quickly into the surrounding skin, where the antigens then elicit in the animals high and protective levels of rabies virus neutralizing antibodies.
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