发明申请
- 专利标题： PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS
- 专利标题（中）： 作为HIV蛋白酶抑制剂的哌嗪衍生物
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申请号： US14908421申请日： 2014-07-29
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公开(公告)号： US20160159752A1公开(公告)日： 2016-06-09
- 发明人: Peter D. Williams , John A. McCauley , David Jonathan Bennett , Christopher J. Bungard , Lehua Chang , Michael P. Dwyer , M. Katharine Holloway , Kartik M. Keertikar , H. Marie Loughran , Jessie J. Manikowski , Gregori J. Morriello , Dong-Ming Shen , Edward C. Sherer , Jurgen Schultz , Sherman T. Waddell , Catherine M. Wiscount , Nicolas Zorn , Xin-Jie Chu , Satyanarayana Tummanapalli , Vijayasaradhi Sivalenka , Bin Hu , Tao Ji , Bin Zhong
- 申请人： MERCK SHARP & DOHME CORP. , MSD R&D (CHINA) CO., LTD.
- 申请人地址： US NJ Rahway CN Shanghai
- 专利权人： Merck Sharp & Dohme Corp.,MSD R&D (CHINA) CO., LTD.
- 当前专利权人： Merck Sharp & Dohme Corp.,MSD R&D (CHINA) CO., LTD.
- 当前专利权人地址： US NJ Rahway CN Shanghai
- 优先权： CNPCT/CN2013/000899 20130731
- 国际申请： PCT/US14/48581 WO 20140729
- 主分类号： C07D241/04
- IPC分类号： C07D241/04 ; C07D401/12 ; C07D417/14 ; C07D405/14 ; C07D413/14 ; C07D401/06 ; C07D405/12
摘要：
The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
公开/授权文献
- US09840478B2 Piperazine derivatives as HIV protease inhibitors 公开/授权日：2017-12-12
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