Invention Application
- Patent Title: TGF BETA R ANTAGONISTS
- Patent Title (中): TGFβR拮抗剂
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Application No.: US14977709Application Date: 2015-12-22
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Publication No.: US20160176871A1Publication Date: 2016-06-23
- Inventor: Brian E. Fink , Yufen Zhao , Robert M. Borzilleri , Liping Zhang , Kyoung S. Kim , Muthoni G. Kamau , Andrew J. Tebben
- Applicant: Bristol-Myers Squibb Company
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/506 ; A61K31/4709 ; A61K31/501 ; A61K31/4985 ; A61K31/5377 ; A61K31/496 ; A61K31/541 ; A61K31/437 ; C07D487/04
Abstract:
The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Public/Granted literature
- US09708316B2 TGFβR antagonists Public/Granted day:2017-07-18
Information query
