发明申请
- 专利标题： TGF BETA R ANTAGONISTS
- 专利标题（中）： TGFβR拮抗剂
-
申请号： US14977709申请日： 2015-12-22
-
公开(公告)号： US20160176871A1公开(公告)日： 2016-06-23
- 发明人: Brian E. Fink , Yufen Zhao , Robert M. Borzilleri , Liping Zhang , Kyoung S. Kim , Muthoni G. Kamau , Andrew J. Tebben
- 申请人： Bristol-Myers Squibb Company
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/506 ; A61K31/4709 ; A61K31/501 ; A61K31/4985 ; A61K31/5377 ; A61K31/496 ; A61K31/541 ; A61K31/437 ; C07D487/04
摘要：
The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
公开/授权文献
- US09708316B2 TGFβR antagonists 公开/授权日：2017-07-18
信息查询
