Invention Application
- Patent Title: AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS
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Application No.: US15058023Application Date: 2016-03-01
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Publication No.: US20160176874A1Publication Date: 2016-06-23
- Inventor: Jennifer R. ALLEN , Jian J. CHEN , Michael J. FROHN , Matthew R. KALLER , Qingyian LIU , Thomas T. NGUYEN , Alexander J. PICKRELL , Wenyuan QIAN , Robert M. RZASA , Wenge ZHONG
- Applicant: AMGEN INC.
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D403/14 ; C07D401/14

Abstract:
Azetidine and piperidine compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Public/Granted literature
- US09493459B2 Azetidine and piperidine compounds useful as PDE10 inhibitors Public/Granted day:2016-11-15
Information query