Invention Application
US20160185785A1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
有权
吡咯和吡唑并嘧啶作为UBIQUITIN特异性蛋白酶7抑制剂
- Patent Title: PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
- Patent Title (中): 吡咯和吡唑并嘧啶作为UBIQUITIN特异性蛋白酶7抑制剂
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Application No.: US14982127Application Date: 2015-12-29
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Publication No.: US20160185785A1Publication Date: 2016-06-30
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , Darby Rye Schmidt , David Joseph Guerin , Justin A. Caravella , R. Bruce Diebold , Anna Ericsson , David Lancia, JR.
- Applicant: Forma Therapeutics, Inc.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.
Public/Granted literature
- US09902728B2 Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors Public/Granted day:2018-02-27
Information query
