An electronic device may be provided with wireless circuitry. The wireless circuitry may include one or more antennas. An antenna may have an antenna feed that is coupled to a radio-frequency transceiver with a transmission line. An impedance matching circuit may be coupled to the antenna feed to match the impedance of the transmission line and the antenna. The impedance matching circuit and tunable circuitry in the antenna may be formed using integrated circuits. Each integrated circuit may include switching circuitry that is used in switching components such as inductors and capacitors into use. Sensors such as temperature sensors, current and voltage sensors, power sensors, and impedance sensors may be integrated into the integrated circuits. Each integrated circuit may store settings for the switching circuitry and may include communications and control circuitry for communicating with external circuits and processing sensor data.