Invention Application
US20160207918A1 SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE
INHIBITORS
审中-公开
带有蛋白酶抑制剂的取代的氮杂双环戊哌嗪衍生物
- Patent Title: SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES WITH PROTEASE INHIBITORS
- Patent Title (中): 带有蛋白酶抑制剂的取代的氮杂双环戊哌嗪衍生物
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Application No.: US15071329Application Date: 2016-03-16
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Publication No.: US20160207918A1Publication Date: 2016-07-21
- Inventor: Tao Wang , Zhongxing Zhang , Nicholas A. Meanwell , John F. Kadow , Zhiwei Yin , Qiufen May Xue , Alicia Regueiro-Ren , John D. Matiskella , Yasutsugu Ueda
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D491/048
Abstract:
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives having the Formula I: wherein Q is These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
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